Explore 23andMe genetic reports.

Take some time to download the report examples that interest you to better understand the types of information your patients receive and may wish to share with you.

Genetic Health Risks

Each Genetic Health Risk report describes if a person has variants associated with a higher risk of developing a disease, but does not describe a person’s overall risk of developing the disease. These reports are not intended to tell a person anything about his or her current state of health, or to be used to make medical decisions, including whether or not he or she should take a medication or how much of a medication should be taken.

Genetic Health Risk reports package insert

White Paper 23-15: Scientific Standards for 23andMe’s Health and Trait Reports

Possible test results
Report Gene Variants Best Studied Ethnicities
Report Age-Related Macular Degeneration GeneCFH, ARMS2 Variants2 Relevant Ethnicities All ethnicities but best studied in Europeans
Report Alpha-1 Antitrypsin Deficiency GeneSERPINA1 Variants2 Relevant Ethnicities European
Report Celiac Disease GeneHLA-DQA1, HLA-DQB1 Variants2 Relevant Ethnicities All ethnicities but best studied in Europeans
Report Hereditary Hemochromatosis (HFE-Related) GeneHFE Variants2 Relevant Ethnicities Europeans
Report Hereditary Thrombophilia GeneF2, F5 Variants2 Relevant Ethnicities European
Report Late-Onset Alzheimer’s Disease GeneAPOE Variants1 Relevant Ethnicities European
Report Parkinson’s Disease GeneLRRK2, GBA Variants2 Relevant Ethnicities European, Ashkenazi Jewish, North African Berber

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Carrier Status

These reports include genetic variants that have been linked to recessive conditions and provide insight into carrier status for the conditions listed below. These reports include only a subset of possible variants that may be linked to a condition, and it is possible to have other variants not included in these reports. Those with a family history of any of these conditions or increased risk based on ethnicity or family origin and are considering having children should discuss options for comprehensive testing with their healthcare provider.

Note: Sample reports do not cover all possible test result outcomes, and for many reports, residual risk estimates vary by ethnicity.

Carrier Status reports package insert

White Paper 23-11: Estimating Carrier Frequency, Carrier Detection Rate and Post-Test Carrier Risk for Recessive Disorders

Possible test results†
Report Gene Variants Relevant Ethnicities
Report Agenesis of the Corpus Callosum with Peripheral Neuropathy GeneSLC12A6 Variants1 Relevant Ethnicities French Canadian
Report ARSACS GeneSACS Variants1 Relevant Ethnicities French Canadian
Report Autosomal Recessive Polycystic Kidney Disease GenePKHD1 Variants3 Relevant Ethnicities Not applicable
Report Beta Thalassemia and Related Hemoglobinopathies GeneHBB Variants10 Relevant Ethnicities Cypriot, Greek, Italian, Sicilian, Sardinian
Report Bloom Syndrome GeneBLM Variants1 Relevant Ethnicities Ashkenazi Jewish
Report Canavan Disease GeneASPA Variants1 Relevant Ethnicities Ashkenazi Jewish
Report Congenital Disorder of Glycosylation Type 1a (PMM2-CDG) GenePMM2 Variants2 Relevant Ethnicities Danish
Report Cystic Fibrosis GeneCFTR Variants28 Relevant Ethnicities European, Hispanic/Latino, Ashkenazi Jewish
Report D-Bifunctional Protein Deficiency GeneHSD17B4 Variants2 Relevant Ethnicities Not applicable
Report Dihydrolipoamide Dehydrogenase Deficiency GeneDLD Variants1 Relevant Ethnicities Ashkenazi Jewish
Report Familial Dysautonomia GeneIKBKAP Variants1 Relevant Ethnicities Ashkenazi Jewish
Report Fanconi Anemia Group C GeneFANCC Variants3 Relevant Ethnicities Ashkenazi Jewish
Report Gaucher Disease Type 1 GeneGBA Variants3 Relevant Ethnicities Ashkenazi Jewish
Report Glycogen Storage Disease Type Ia GeneG6PC Variants1 Relevant Ethnicities Ashkenazi Jewish
Report Glycogen Storage Disease Type Ib GeneSLC37A4 Variants2 Relevant Ethnicities Not applicable
Report GRACILE Syndrome GeneBCS1L Variants1 Relevant Ethnicities Finnish
Report Hereditary Fructose Intolerance GeneALDOB Variants3 Relevant Ethnicities European
Report Herlitz Junctional Epidermolysis Bullosa (LAMB3-Related) GeneLAMB3 Variants3 Relevant Ethnicities Not applicable
Report Leigh Syndrome, French Canadian Type GeneLRPPRC Variants1 Relevant Ethnicities French Canadian
Report Limb-Girdle Muscular Dystrophy Type 2D GeneSGCA Variants1 Relevant Ethnicities Finnish
Report Limb-Girdle Muscular Dystrophy Type 2E GeneSGCB Variants1 Relevant Ethnicities Southern Indiana Amish
Report Limb-Girdle Muscular Dystrophy Type 2I GeneFKRP Variants1 Relevant Ethnicities European
Report Maple Syrup Urine Disease Type 1B GeneBCKDHB Variants2 Relevant Ethnicities Ashkenazi Jewish
Report MCAD Deficiency GeneACADM Variants3 Relevant Ethnicities Northern European
Report Mucolipidosis Type IV GeneMCOLN1 Variants1 Relevant Ethnicities Ashkenazi Jewish
Report Neuronal Ceroid Lipofuscinosis (CLN5-Related) GeneCLN5 Variants1 Relevant Ethnicities Finnish
Report Neuronal Ceroid Lipofuscinosis (PPT1-Related) GenePPT1 Variants3 Relevant Ethnicities Finnish
Report Niemann-Pick Disease Type A GeneSMPD1 Variants3 Relevant Ethnicities Ashkenazi Jewish
Report Nijmegen Breakage Syndrome GeneNBN Variants1 Relevant Ethnicities Eastern European
Report Nonsyndromic Hearing Loss and Deafness, DFNB1 (GJB2-Related) GeneGJB2 Variants2 Relevant Ethnicities Ashkenazi Jewish, European
Report Pendred Syndrome and DFNB4 Hearing Loss GeneSLC26A4 Variants6 Relevant Ethnicities Not applicable
Report Phenylketonuria and Related Disorders GenePAH Variants23 Relevant Ethnicities Northern European
Report Primary Hyperoxaluria Type 2 GeneGRHPR Variants1 Relevant Ethnicities European
Report Rhizomelic Chondrodysplasia Punctata Type 1 GenePEX7 Variants1 Relevant Ethnicities Not applicable
Report Salla Disease GeneSLC17A5 Variants1 Relevant Ethnicities Finnish, Swedish
Report Sickle Cell Anemia GeneHBB Variants1 Relevant Ethnicities African
Report Sjögren-Larsson Syndrome GeneALDH3A2 Variants1 Relevant Ethnicities Swedish
Report Tay-Sachs Disease GeneHEXA Variants4 Relevant Ethnicities Ashkenazi Jewish, Cajun
Report Tyrosinemia Type I GeneFAH Variants4 Relevant Ethnicities French Canadian, Finnish
Report Usher Syndrome Type 1F GenePCDH15 Variants1 Relevant Ethnicities Ashkenazi Jewish
Report Usher Syndrome Type 3A GeneCLRN1 Variants1 Relevant Ethnicities Ashkenazi Jewish
Report Zellweger Syndrome Spectrum (PEX1-Related) GenePEX1 Variants1 Relevant Ethnicities Not applicable

Wellness reports

These reports describe how genetics influence traits and conditions related to lifestyle and environment.

White Paper 23-17: The Science Behind 23andMe’s Genetic Weight Report

White Paper 23-15: Scientific Standards for 23andMe’s Health and Trait Reports

Report Gene Variants Relevant Ethnicities
Report Alcohol Flush GeneNot applicable VariantsNot applicable Relevant Ethnicities
Report Caffeine Metabolism GeneNot applicable VariantsNot applicable Relevant Ethnicities
Report Deep Sleep GeneNot applicable VariantsNot applicable Relevant Ethnicities
Report Genetic Weight GeneNot applicable VariantsNot applicable Relevant Ethnicities
Report Lactose Intolerance GeneNot applicable VariantsNot applicable Relevant Ethnicities
Report Muscle Performance GeneNot applicable VariantsNot applicable Relevant Ethnicities
Report Saturated Fat and Weight GeneNot applicable VariantsNot applicable Relevant Ethnicities
Report Sleep Movement GeneNot applicable VariantsNot applicable Relevant Ethnicities

Ancestry reports

These reports help consumers learn about their origins and ancient ancestors based on their DNA.

White Paper 23-16: Ancestry Composition: A Novel, Efficient Pipeline for Ancestry Deconvolution

White Paper 23-05: Neanderthal Ancestry Inference

White Paper 23-13: yHaplo™ | Identifying Y-Chromosome Haplogroups in Arbitrarily Large Samples of Sequenced or Genotyped Men

Report Gene Variants Relevant Ethnicities
Report Ancestry Composition GeneNot applicable VariantsNot applicable Relevant Ethnicities
Report Maternal Haplogroup GeneNot applicable VariantsNot applicable Relevant Ethnicities
Report Neanderthal Ancestry GeneNot applicable VariantsNot applicable Relevant Ethnicities
Report Paternal Haplogroup GeneNot applicable VariantsNot applicable Relevant Ethnicities
Report Your DNA Family GeneNot applicable VariantsNot applicable Relevant Ethnicities

Traits reports

These reports are a fun way for consumers to learn about how genetics influence traits like eye color, hair texture and taste preference.

White Paper 23-15: Scientific Standards for 23andMe’s Health and Trait Reports

Report Gene Variants Relevant Ethnicities
Report Asparagus Odor Detection GeneNot applicable VariantsNot applicable Relevant Ethnicities
Report Back Hair (available for men only) GeneNot applicable VariantsNot applicable Relevant Ethnicities
Report Bald Spot (available for men only) GeneNot applicable VariantsNot applicable Relevant Ethnicities
Report Digit Ratio^ GeneNot applicable VariantsNot applicable Relevant Ethnicities
Report Earlobe Type GeneNot applicable VariantsNot applicable Relevant Ethnicities
Report Earwax Type GeneNot applicable VariantsNot applicable Relevant Ethnicities
Report Eye Color GeneNot applicable VariantsNot applicable Relevant Ethnicities
Report Facial Features^ GeneNot applicable VariantsNot applicable Relevant Ethnicities
Report Hair Color^ GeneNot applicable VariantsNot applicable Relevant Ethnicities
Report Hair Curliness GeneNot applicable VariantsNot applicable Relevant Ethnicities
Report Male Hair Loss (available for men only) GeneNot applicable VariantsNot applicable Relevant Ethnicities
Report Newborn Hair Amount GeneNot applicable VariantsNot applicable Relevant Ethnicities
Report Photic Sneeze Reflex GeneNot applicable VariantsNot applicable Relevant Ethnicities
Report Skin Pigmentation^ GeneNot applicable VariantsNot applicable Relevant Ethnicities
Report Taste Preference and Perception GeneNot applicable VariantsNot applicable Relevant Ethnicities
Report Widow’s Peak GeneNot applicable VariantsNot applicable Relevant Ethnicities

 

^ multiple trait reports included

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Limitations associated with genetic raw data.

Our customers have access to their raw genetic data, which they can view or download from their 23andMe account. This data has undergone a general quality review; however, only a subset of markers have been individually validated for accuracy. As such, the data from 23andMe’s Browse Raw Data feature is suitable only for research and educational and informational use and not for medical, diagnostic or other use.

The raw data could include sensitive information. Within the data, your patients could discover sensitive information about themselves and family members with whom they share their DNA. For example, comparing data between family members could reveal non-paternity.

FAQ

Questions? Contact us at medical@23andme.com.

* The 23andMe PGS test uses qualitative genotyping to detect clinically relevant variants in the genomic DNA of adults from saliva collected using an FDA-cleared collection device (Oragene·DX model OGD-500.001) for the purpose of reporting and interpreting genetic health risks and reporting carrier status. It is not intended to diagnose any disease. The relevance of each report varies based on ethnicity. Each Genetic Health Risk report describes if a person has variants associated with a higher risk of developing a disease, but does not describe a person’s overall risk of developing the disease. These reports are intended to provide genetic information that can be used to inform lifestyle decisions and conversations with healthcare professionals, but are not intended to tell you anything about your current state of health, or to be used to make medical decisions, including whether or not you should take a medication or how much of a medication you should take. Any diagnostic or treatment decisions should be based on testing or other information deemed appropriate by a healthcare professional. Our Carrier Status reports can be used to determine carrier status, but cannot determine if you have two copies of any genetic variant. These carrier reports are not intended to tell you anything about your risk for developing a disease in the future or anything about the health of your fetus, or your newborn child’s risk of developing a particular disease later in life. For Gaucher Disease Type 1, we provide a single report that includes information on both carrier status and genetic health risk.